Representative Publications
Anti-drug vaccines
Stone AE, Scheuermann SE, Haile CN, Cuny GD, Velasquez ML, Linhuber JP, Duddupudi A, Vigliaturo J, Pravetoni M, Kosten TA, Kosten TR, Norton EB. Novel fentanyl conjugate vaccine by injected or mucosal delivery with dmLT or LTA1 adjuvants implicates IgA in protection from drug challenge. NPJ Vaccines, in press.
Ohia-Nwoko O, Kosten TA, Haile CN. (2016) Animal models and the development of vaccines to treat substance use disorders. Int Rev Neurobiol, 126:263-291. Link to article
Kosten TA, Shen XY, O'Malley PW, Kinsey BM, Lykissa ED, Orson FM, Kosten TR. (2013) A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats. Prog Neuropsychopharmacol Biol Psychiatry. 45:223-9. Link to article
Shen XY, Kosten TA, Lopez AY, Kinsey BM, Kosten TR, Orson FM. (2013) A vaccine against methamphetamine attenuates its behavioral effects in mice. Drug Alcohol Depend. 129(1-2):41-8. Link to article
Gut microbiota
Forouzan S, Hoffman KL, Kosten TA. (2021) Methamphetamine exposure and its cessation alter gut microbiota and induce depressive-like behavioral effects on rats. Psychopharmacology (Berl). 238(1):281-292. Link to article
Pharmacological manipulations
Nieto SJ, Quave CB, Kosten TA. (2018) Naltrexone alters alcohol self-administration behaviors and hypothalamic-pituitary-adrenal axis activity in a sex-dependent manner in rats. Pharmacol Biochem Behav. 167:50-59. Link to article
Haile CN, Kosten TA. (2017) The peroxisome proliferator-activated receptor alpha agonist fenofibrate attenuates alcohol self-administration in rats. Neuropharmacology. 116:364-370. Link to article.
Gomez, JL, Cunningham CL, Finn DA, Young EA, Helpenstell LK, Schuette LM, Fidler TL, Kosten TA, Ryabinin AE. (2015) Differential effects of ghrelin antagonists on alcohol drinking and reinforcement in mouse and rat models of alcohol dependence. Neuropharmacology, 97:182-93. Link to article
Developmental and Epigenetic Research
Nieto SJ, Kosten TA. (2019) Who's your daddy? Behavioral and epigenetic consequences of paternal drug exposure. Int J Dev Neurosci. 78:109-121. Link to article
Walters H, Kosten TA. (2019) Early life stress and the propensity to develop addictive behaviors, Int J Dev Neurosci. 78:156-169. Link to article
Nieto SJ, Patriquin MA, Nielsen DA, Kosten TA. (2016) Don’t worry; be informed about the epigenetics of anxiety. Pharmacol Biochem Behav, 146-147:60-72. Link to article
Kosten TA, Huang W, Nielsen DA. (2014) Sex and litter effects on anxiety and DNA methylation levels of stress and neurotrophin genes in adolescent rats. Dev Psychobiol. Apr;56(3):392-406. Link to article
Stress, Emotion, Sex Differences
Quave, C.B., Nieto, S.J., Haile, C.N. & Kosten, TA. (2021) Immune receptor toll-like receptor 4 contributes to stress-induced affective responses in a sex-specific manner. Brain Behav, Immunity - Health, 14. In press. Link to article
Nieto SJ, Kosten TA. (2017) Female Sprague-Dawley rats display greater appetitive and consummatory responses to alcohol. Behav Brain Res, 327:155-161. Link to article
Ohia-Nwoko O, Haile CN, Kosten TA. (2017) Sex differences in the acute locomotor response to methamphetamine in BALB/c mice. Behav Brain Res, 327:94-97. Link to article